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High doses of B12, often used to treat deficiencies, may cause side effects such as headaches, nausea, diarrhea, fatigue or weakness, and tingling in the hands and feet

The ability of Epitalon to permeate the cell membrane and enter the nucleus has been demonstrated [20], thus suggesting that its activity may be associated with cytoplasmic and nuclear components

There is also the potential for use in neurodegenerative diseases, wherein oxidative stress plays a key role, though current evidence is not conclusive and more research is needed to establish efficacy in this regard

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Remember that your body is not able to store vitamin B12 for long periods of time